Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH90545.1Formyl-CoA transferase; Function of strongly homologous gene; enzyme; Belongs to the CoA-transferase III family. (414 aa)    
Predicted Functional Partners:
CCH90546.1
Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.842
icmF
Methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.731
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
    
 0.728
mutB
Methylmalonyl-CoA mutase large subunit (MCM-alpha); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.690
fdhA2
Formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 
 0.655
matC
Dicarboxylate-carrier protein; Function of strongly homologous gene; carrier.
       0.588
CCH90901.1
Hydroxymethylglutaryl-CoA lyase; Function of strongly homologous gene; enzyme.
 
  0.512
CCH90543.1
Serine-glyoxylate aminotransferase; Function of strongly homologous gene; enzyme.
    
 0.510
paaZ
Fused aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.504
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.451
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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