STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trwC-2Conjugative relaxase TrwC; Function of strongly homologous gene; enzyme. (1208 aa)    
Predicted Functional Partners:
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
 
 0.840
CCH87736.1
Membrane protein of unknown function, putative kinase domain; No homology to any previously reported sequences.
  
    0.712
CCH87746.1
Homologs of previously reported genes of unknown function.
  
    0.684
CCH90777.1
HNH endonuclease; Function of strongly homologous gene; enzyme.
  
    0.607
CCH87301.1
HNH endonuclease; Function of strongly homologous gene; enzyme.
  
     0.570
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.561
CCH90685.1
Putative HNH endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.556
CCH89081.1
Putative HNH endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.550
CCH89013.1
Homologs of previously reported genes of unknown function.
  
   
 0.545
CCH88009.1
Putative ATP-dependent exoDNAse (Exonuclease V), alpha subunit/helicase superfamily I member; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
  0.515
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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