node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS78021.1 | SIS81053.1 | SAMN05421788_1011163 | SAMN05421788_1011352 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 0.802 |
SIS78021.1 | SIT18891.1 | SAMN05421788_1011163 | SAMN05421788_104485 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.849 |
SIS78021.1 | SIT32424.1 | SAMN05421788_1011163 | SAMN05421788_111132 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.860 |
SIS78021.1 | SIT34779.1 | SAMN05421788_1011163 | SAMN05421788_11912 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.859 |
SIS78021.1 | fabZ | SAMN05421788_1011163 | SAMN05421788_101527 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.666 |
SIS78021.1 | kdsB | SAMN05421788_1011163 | SAMN05421788_1011084 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.869 |
SIS78021.1 | lpxD | SAMN05421788_1011163 | SAMN05421788_101526 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.819 |
SIS78021.1 | lpxK | SAMN05421788_1011163 | SAMN05421788_107199 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.864 |
SIS81053.1 | SIS78021.1 | SAMN05421788_1011352 | SAMN05421788_1011163 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.802 |
SIS81053.1 | SIS81145.1 | SAMN05421788_1011352 | SAMN05421788_1011357 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | UDP-2,3-diacylglucosamine hydrolase. | 0.921 |
SIS81053.1 | SIT18891.1 | SAMN05421788_1011352 | SAMN05421788_104485 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.707 |
SIS81053.1 | SIT32424.1 | SAMN05421788_1011352 | SAMN05421788_111132 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.756 |
SIS81053.1 | SIT34779.1 | SAMN05421788_1011352 | SAMN05421788_11912 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.981 |
SIS81053.1 | fabZ | SAMN05421788_1011352 | SAMN05421788_101527 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.987 |
SIS81053.1 | kdsB | SAMN05421788_1011352 | SAMN05421788_1011084 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.791 |
SIS81053.1 | lpxD | SAMN05421788_1011352 | SAMN05421788_101526 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.924 |
SIS81053.1 | lpxK | SAMN05421788_1011352 | SAMN05421788_107199 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.794 |
SIS81145.1 | SIS81053.1 | SAMN05421788_1011357 | SAMN05421788_1011352 | UDP-2,3-diacylglucosamine hydrolase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 0.921 |
SIS81145.1 | SIT18891.1 | SAMN05421788_1011357 | SAMN05421788_104485 | UDP-2,3-diacylglucosamine hydrolase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.453 |
SIS81145.1 | SIT32424.1 | SAMN05421788_1011357 | SAMN05421788_111132 | UDP-2,3-diacylglucosamine hydrolase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.434 |