STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFT50441.13-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). (168 aa)    
Predicted Functional Partners:
SFT50455.1
Sialic acid synthase.
  
 0.987
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
 0.972
SFT50473.1
Spore coat polysaccharide biosynthesis protein SpsF.
 
    0.822
SFT66870.1
rfaE bifunctional protein, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
 
      0.821
SFT50424.1
Hypothetical protein.
       0.773
SFT50489.1
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
       0.494
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.448
SFT88746.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.446
SFT90869.1
cation:H+ antiporter.
      0.446
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
  
 0.418
Your Current Organism:
Lishizhenia tianjinensis
NCBI taxonomy Id: 477690
Other names: CGMCC 1.7005, JCM 15141, L. tianjinensis, Lishizhenia tianjinensis Chen et al. 2009, marine bacterium H6, strain H6
Server load: medium (56%) [HD]