SFT70296.1 protein (Lishizhenia tianjinensis)

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

SFT70296.1

Hypothetical protein. (346 aa)

Predicted Functional Partners:

SFT80841.1

0.877

SFT76376.1

0.775

SFT84254.1

0.775

SFT76389.1

0.744

SFT88573.1

0.743

SFT74307.1

0.742

SFT62529.1

0.733

SFT67993.1

0.733

SFT86298.1

0.733

SFT67903.1

0.730

Your Current Organism:

Lishizhenia tianjinensis

NCBI taxonomy Id: 477690
Other names: CGMCC 1.7005, JCM 15141, L. tianjinensis, Lishizhenia tianjinensis Chen et al. 2009, marine bacterium H6, strain H6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFT62529.1	SFT67903.1	SAMN05216474_1392	SAMN05216474_1744	Penicillin-binding protein 2.	Cell division protein FtsQ.	0.859
SFT62529.1	SFT67993.1	SAMN05216474_1392	SAMN05216474_1752	Penicillin-binding protein 2.	Cell division protein FtsI (penicillin-binding protein 3).	0.951
SFT62529.1	SFT70296.1	SAMN05216474_1392	SAMN05216474_1919	Penicillin-binding protein 2.	Hypothetical protein.	0.733
SFT62529.1	SFT76389.1	SAMN05216474_1392	SAMN05216474_2252	Penicillin-binding protein 2.	Hypothetical protein.	0.733
SFT67903.1	SFT62529.1	SAMN05216474_1744	SAMN05216474_1392	Cell division protein FtsQ.	Penicillin-binding protein 2.	0.859
SFT67903.1	SFT67993.1	SAMN05216474_1744	SAMN05216474_1752	Cell division protein FtsQ.	Cell division protein FtsI (penicillin-binding protein 3).	0.975
SFT67903.1	SFT70296.1	SAMN05216474_1744	SAMN05216474_1919	Cell division protein FtsQ.	Hypothetical protein.	0.730
SFT67903.1	SFT76389.1	SAMN05216474_1744	SAMN05216474_2252	Cell division protein FtsQ.	Hypothetical protein.	0.730
SFT67903.1	SFT86298.1	SAMN05216474_1744	SAMN05216474_2821	Cell division protein FtsQ.	Protein of unknown function.	0.886
SFT67993.1	SFT62529.1	SAMN05216474_1752	SAMN05216474_1392	Cell division protein FtsI (penicillin-binding protein 3).	Penicillin-binding protein 2.	0.951
SFT67993.1	SFT67903.1	SAMN05216474_1752	SAMN05216474_1744	Cell division protein FtsI (penicillin-binding protein 3).	Cell division protein FtsQ.	0.975
SFT67993.1	SFT70296.1	SAMN05216474_1752	SAMN05216474_1919	Cell division protein FtsI (penicillin-binding protein 3).	Hypothetical protein.	0.733
SFT67993.1	SFT76389.1	SAMN05216474_1752	SAMN05216474_2252	Cell division protein FtsI (penicillin-binding protein 3).	Hypothetical protein.	0.733
SFT70296.1	SFT62529.1	SAMN05216474_1919	SAMN05216474_1392	Hypothetical protein.	Penicillin-binding protein 2.	0.733
SFT70296.1	SFT67903.1	SAMN05216474_1919	SAMN05216474_1744	Hypothetical protein.	Cell division protein FtsQ.	0.730
SFT70296.1	SFT67993.1	SAMN05216474_1919	SAMN05216474_1752	Hypothetical protein.	Cell division protein FtsI (penicillin-binding protein 3).	0.733
SFT70296.1	SFT74307.1	SAMN05216474_1919	SAMN05216474_2090	Hypothetical protein.	TonB-dependent Receptor Plug Domain.	0.742
SFT70296.1	SFT76376.1	SAMN05216474_1919	SAMN05216474_2251	Hypothetical protein.	Peptidase family C25.	0.775
SFT70296.1	SFT76389.1	SAMN05216474_1919	SAMN05216474_2252	Hypothetical protein.	Hypothetical protein.	0.744
SFT70296.1	SFT80841.1	SAMN05216474_1919	SAMN05216474_2449	Hypothetical protein.	Cell surface protein SprA.	0.877

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.916

expected number of edges:

29

PPI enrichment p-value:

0.0016

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006544

Glycine metabolic process

4 of 8

2.2

2.29

3.30e-05

GO:0019464

Glycine decarboxylation via glycine cleavage system

3 of 4

2.37

1.76

0.00051

GO:0006189

De novo IMP biosynthetic process

3 of 14

1.83

1.39

0.0015

GO:0035999

Tetrahydrofolate interconversion

2 of 3

2.32

1.31

0.0037

GO:0009156

Ribonucleoside monophosphate biosynthetic process

4 of 37

1.53

1.29

0.0011

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

4 of 8

2.2

2.41

1.84e-05

GO:0016741

Transferase activity, transferring one-carbon groups

5 of 61

1.41

1.36

0.00031

GO:0019238

Cyclohydrolase activity

2 of 5

2.1

0.73

0.0440

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005960

Glycine cleavage complex

2 of 3

2.32

1.22

0.0055

GO:0005829

Cytosol

7 of 303

0.86

0.71

0.0012

GO:0005737

Cytoplasm

9 of 1173

0.38

0.26

0.0472

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:31410034

(2019) Staphyloxanthin: a potential target for antivirulence therapy.

3 of 10

1.98

1.56

0.00079

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1866

Glycine catabolic process

4 of 5

2.4

2.76

5.29e-06

CL:839

De novo IMP biosynthetic process

3 of 8

2.07

1.61

0.00075

CL:834

Nucleoside monophosphate biosynthetic process, and Pyrimidine metabolism

4 of 57

1.35

0.99

0.0040

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00670

One carbon pool by folate

5 of 17

1.97

2.95

3.19e-07

map00260

Glycine, serine and threonine metabolism

4 of 46

1.44

1.37

0.00033

map00630

Glyoxylate and dicarboxylate metabolism

4 of 49

1.41

1.35

0.00033

map01200

Carbon metabolism

6 of 114

1.22

1.33

3.39e-05

map01110

Biosynthesis of secondary metabolites

8 of 436

0.76

0.66

0.00029

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005960

Glycine cleavage complex

2 of 3

2.32

0.88

0.0239

GOCC:0005737

Cytoplasm

9 of 946

0.48

0.31

0.0352

GOCC:0005622

Intracellular

10 of 1285

0.39

0.28

0.0352

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

4 of 17

1.87

1.96

6.97e-05

KW-0554

One-carbon metabolism

2 of 5

2.1

0.9

0.0210

KW-0511

Multifunctional enzyme

2 of 10

1.8

0.71

0.0436

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