STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gmk2Unannotated protein. (180 aa)    
Predicted Functional Partners:
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.947
apt
Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.947
xpt
Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.946
pyk
Unannotated protein; Belongs to the pyruvate kinase family.
  
 
 0.933
gmk
Unannotated protein; Essential for recycling GMP and indirectly, cGMP.
  
  
 
0.927
RelA
Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.919
guaC
Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
    
 0.911
hpt
Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.908
Hpt2
Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.908
NrdF
Unannotated protein.
     
 0.904
Your Current Organism:
Lactobacillus crispatus
NCBI taxonomy Id: 47770
Other names: ATCC 33820, CCUG 30722, CIP 102990, CIPP II, DSM 20584, Eubacterium crispatum, L. crispatus, LMG 9479, LMG:9479, VPI 3199
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.