Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCR75_009418Tudor-knot domain-containing protein. (605 aa)    
Predicted Functional Partners:
CCR75_006715
PHD-type domain-containing protein.
    
 0.980
CCR75_002327
Uncharacterized protein.
   
 0.913
CCR75_006160
SWIB domain-containing protein.
    
 0.855
CCR75_008013
WD_REPEATS_REGION domain-containing protein.
    
 0.728
CCR75_000654
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.714
CCR75_008390
Uncharacterized protein; Belongs to the actin family.
    
 0.712
CCR75_006416
Uncharacterized protein; Belongs to the actin family.
    
 0.712
CCR75_001601
HMG box domain-containing protein.
    
 0.708
CCR75_004117
HMG box domain-containing protein.
    
 0.708
CCR75_000941
Histone H2A; Belongs to the histone H2A family.
    
  0.687
Your Current Organism:
Bremia lactucae
NCBI taxonomy Id: 4779
Other names: B. lactucae, Bremia lactucae Regel, lettuce downy mildew
Server load: low (14%) [HD]