Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daud_1981PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2; KEGG: tte:TTE1276 Endonuclease IV. (287 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.621
Daud_1588
PFAM: protein of unknown function RIO1; protein kinase; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; KEGG: mta:Moth_0912 serine/threonine protein kinase.
     
 0.600
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.585
Daud_1982
PFAM: extracellular solute-binding protein, family 5; KEGG: dsy:DSY0502 hypothetical protein.
       0.546
Daud_1278
Metallophosphoesterase; PFAM: SMC domain protein; metallophosphoesterase; KEGG: chy:CHY_0945 Ser/Thr protein phosphatase family protein.
     
 0.507
hisI
PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: swo:Swol_1764 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
      
 0.466
Daud_1980
TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; KEGG: chy:CHY_1622 pyruvoyl-dependent arginine decarboxylase.
       0.462
Daud_1235
PFAM: protein of unknown function DUF366; KEGG: chy:CHY_0953 hypothetical protein.
  
    0.435
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.433
Daud_1978
TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mta:Moth_1815 agmatinase, putative; Belongs to the arginase family.
       0.423
Your Current Organism:
Desulforudis audaxviator
NCBI taxonomy Id: 477974
Other names: C. Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator str. MP104C, Candidatus Desulforudis audaxviator strain MP104C
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