| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A7456_01070 | OBX84128.1 | A7456_01070 | A7456_03460 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.616 |
| A7456_01070 | OBX87872.1 | A7456_01070 | A7456_07455 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.544 |
| A7456_01070 | dnaJ | A7456_01070 | A7456_02945 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.410 |
| A7456_01070 | radA | A7456_01070 | A7456_05305 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.862 |
| A7456_01070 | recA | A7456_01070 | A7456_01075 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.988 |
| A7456_01070 | recF | A7456_01070 | A7456_03015 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Hypothetical protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.489 |
| A7456_01070 | ruvA | A7456_01070 | A7456_04185 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.559 |
| A7456_01070 | ruvB | A7456_01070 | A7456_08395 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.489 |
| A7456_01070 | topA | A7456_01070 | A7456_01805 | Adhesin; Modulates RecA activity; Belongs to the RecX family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.553 |
| OBX84128.1 | A7456_01070 | A7456_03460 | A7456_01070 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Adhesin; Modulates RecA activity; Belongs to the RecX family. | 0.616 |
| OBX84128.1 | OBX87872.1 | A7456_03460 | A7456_07455 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.628 |
| OBX84128.1 | dnaJ | A7456_03460 | A7456_02945 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.578 |
| OBX84128.1 | radA | A7456_03460 | A7456_05305 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.609 |
| OBX84128.1 | recA | A7456_03460 | A7456_01075 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.868 |
| OBX84128.1 | recF | A7456_03460 | A7456_03015 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.574 |
| OBX84128.1 | ruvA | A7456_03460 | A7456_04185 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.626 |
| OBX84128.1 | ruvB | A7456_03460 | A7456_08395 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.575 |
| OBX84128.1 | topA | A7456_03460 | A7456_01805 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.627 |
| OBX84128.1 | uvrC | A7456_03460 | A7456_07505 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.605 |
| OBX87872.1 | A7456_01070 | A7456_07455 | A7456_01070 | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | Adhesin; Modulates RecA activity; Belongs to the RecX family. | 0.544 |
