STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIR64215.1Pyrimidine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.908
KIR62017.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
     
 0.900
KIR66471.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.711
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.690
KIR64216.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
     
 0.640
KIR63104.1
Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.625
RibD
DeoR faimly transcriptional regulator; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.613
GcvT
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.572
KIR66653.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.477
KIR64722.1
Deaminase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.452
Your Current Organism:
Micromonospora carbonacea
NCBI taxonomy Id: 47853
Other names: ATCC 27114, ATCC 27115, DSM 43168, DSM 43815, IFO 14107, IFO 14108, JCM 3139, M. carbonacea, Micromonospora carbonacea subsp. aurantiaca, Micromonospora carbonacea subsp. carbonacea, NBRC 14108, NRRL 2972
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