STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIR64840.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (118 aa)    
Predicted Functional Partners:
TrxB
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.938
KIR64841.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.824
KIR65858.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.785
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
 
 
 0.541
KIR64842.1
DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
KIR64839.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.524
KIR65480.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.521
KIR65129.1
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.519
KIR66291.1
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.519
GltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.508
Your Current Organism:
Micromonospora carbonacea
NCBI taxonomy Id: 47853
Other names: ATCC 27114, ATCC 27115, DSM 43168, DSM 43815, IFO 14107, IFO 14108, JCM 3139, M. carbonacea, Micromonospora carbonacea subsp. aurantiaca, Micromonospora carbonacea subsp. carbonacea, NBRC 14108, NRRL 2972
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