STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIR65841.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)    
Predicted Functional Partners:
manB
Phosphomannomutase; Converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.969
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
  
 
 0.969
KIR65284.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.933
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.913
glmS
Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.912
GlpX
Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
KIR63185.1
Glucosamine-6-phosphate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.903
KIR65842.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.900
KIR65843.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.825
KIR65084.1
Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.741
Your Current Organism:
Micromonospora carbonacea
NCBI taxonomy Id: 47853
Other names: ATCC 27114, ATCC 27115, DSM 43168, DSM 43815, IFO 14107, IFO 14108, JCM 3139, M. carbonacea, Micromonospora carbonacea subsp. aurantiaca, Micromonospora carbonacea subsp. carbonacea, NBRC 14108, NRRL 2972
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.