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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIR66223.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)    
Predicted Functional Partners:
KIR65720.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
KIR64562.1
3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.975
KIR63271.1
3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.975
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.966
KIR61413.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.961
KIR64965.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.960
KIR65761.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.958
KIR65202.1
acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.957
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.946
KIR64814.1
Citrate synthase 2; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.938
Your Current Organism:
Micromonospora carbonacea
NCBI taxonomy Id: 47853
Other names: ATCC 27114, ATCC 27115, DSM 43168, DSM 43815, IFO 14107, IFO 14108, JCM 3139, M. carbonacea, Micromonospora carbonacea subsp. aurantiaca, Micromonospora carbonacea subsp. carbonacea, NBRC 14108, NRRL 2972
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