STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL65347.1CBS domain-containing protein. (139 aa)    
Predicted Functional Partners:
SCL71211.1
Glutamate synthase (NADH) large subunit.
    
 0.772
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.743
SCL62254.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.647
proS-2
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
    0.606
SCL61377.1
IMP dehydrogenase.
    
 0.590
SCL65351.1
Cysteine desulfuration protein SufE.
       0.517
SCL65356.1
Predicted dithiol-disulfide isomerase, DsbA family.
       0.479
SCL65338.1
Glyoxalase-like domain-containing protein.
       0.436
SCL65332.1
Methyltransferase domain-containing protein.
   
   0.433
gcvP
Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
  0.415
Your Current Organism:
Micromonospora chersina
NCBI taxonomy Id: 47854
Other names: ATCC 53710, DSM 44151, IFO 15963, JCM 9459, M. chersina, NBRC 15963, strain M956-1
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