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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCG38027.1Helix-turn-helix domain-containing protein. (129 aa)    
Predicted Functional Partners:
SCG48462.1
Transcriptional attenuator, LytR family.
   
    0.710
SCG38214.1
Protein of unknown function; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
   
 0.676
SCG38036.1
Serine/threonine protein kinase.
     
 0.650
cobB-2
NAD-dependent protein deacetylase, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
    0.602
cobB-3
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
   
    0.602
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.580
tatA
Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
     0.576
SCG48964.1
Transcriptional regulator, HxlR family.
   
    0.542
SCG54664.1
Transcriptional regulator, HxlR family.
   
    0.542
SCG61794.1
Transcriptional regulator, HxlR family.
   
    0.542
Your Current Organism:
Micromonospora halophytica
NCBI taxonomy Id: 47864
Other names: ATCC 27596, DSM 43171, IFO 14112, JCM 3125, M. halophytica, Micromonospora halophytica subsp. halophytica, NBRC 14112, NRRL 2998
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