STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCG40741.1Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (318 aa)    
Predicted Functional Partners:
SCG56837.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.934
SCG40824.1
L-erythro-3-methylmalyl-CoA dehydratase.
 
 
 0.905
SCG55042.1
L-ribulose 5-phosphate 4-epimerase.
   
    0.895
SCG40569.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.882
accD
acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
 0.835
SCG47095.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
 0.809
SCG33919.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.808
SCG33758.1
(R)-ethylmalonyl-CoA mutase.
 
  
 0.805
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.773
SCG65479.1
propionyl-CoA synthetase.
   
 0.773
Your Current Organism:
Micromonospora halophytica
NCBI taxonomy Id: 47864
Other names: ATCC 27596, DSM 43171, IFO 14112, JCM 3125, M. halophytica, Micromonospora halophytica subsp. halophytica, NBRC 14112, NRRL 2998
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