Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCG61056.1Drug resistance transporter, EmrB/QacA subfamily. (499 aa)    
Predicted Functional Partners:
SCG61042.1
Lysine N6-hydroxylase.
       0.780
SCG61045.1
Protein N-acetyltransferase, RimJ/RimL family.
       0.773
SCG61050.1
Siderophore synthetase component.
       0.773
SCG61036.1
L-2,4-diaminobutyrate decarboxylase.
  
 
  0.750
thyX
Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
  0.530
SCG67659.1
Thymidine kinase.
     
  0.530
SCG36834.1
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.474
SCG61023.1
NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains.
       0.473
SCG58016.1
Hypothetical protein.
     
  0.464
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.464
Your Current Organism:
Micromonospora halophytica
NCBI taxonomy Id: 47864
Other names: ATCC 27596, DSM 43171, IFO 14112, JCM 3125, M. halophytica, Micromonospora halophytica subsp. halophytica, NBRC 14112, NRRL 2998
Server load: low (36%) [HD]