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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCG67199.1Fructokinase. (311 aa)    
Predicted Functional Partners:
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 
 0.895
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.888
SCG33954.1
Glutamine--fructose-6-phosphate transaminase.
  
 
 0.885
SCG42803.1
Mannose-6-phosphate isomerase, type 1.
    
 0.884
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
     
 0.882
SCG41989.1
Fructose-1,6-bisphosphatase II.
    
  0.877
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.875
SCG42789.1
Phospho-glucose isomerase C-terminal SIS domain-containing protein.
    
  0.872
SCG36777.1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.854
SCG45788.1
Fructuronate reductase; Belongs to the mannitol dehydrogenase family.
 
  
 0.848
Your Current Organism:
Micromonospora halophytica
NCBI taxonomy Id: 47864
Other names: ATCC 27596, DSM 43171, IFO 14112, JCM 3125, M. halophytica, Micromonospora halophytica subsp. halophytica, NBRC 14112, NRRL 2998
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