Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCG67199.1Fructokinase. (311 aa)    
Predicted Functional Partners:
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 0.797
SCG33954.1
Glutamine--fructose-6-phosphate transaminase.
  
 
 0.780
SCG45788.1
Fructuronate reductase; Belongs to the mannitol dehydrogenase family.
 
  
 0.775
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
     
 0.774
SCG41989.1
Fructose-1,6-bisphosphatase II.
    
 0.773
SCG42803.1
Mannose-6-phosphate isomerase, type 1.
    
 0.768
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.767
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.756
SCG42789.1
Phospho-glucose isomerase C-terminal SIS domain-containing protein.
     
  0.753
SCG45711.1
2-keto-3-deoxy-phosphogluconate aldolase.
 
 
 0.753
Your Current Organism:
Micromonospora halophytica
NCBI taxonomy Id: 47864
Other names: ATCC 27596, DSM 43171, IFO 14112, JCM 3125, M. halophytica, Micromonospora halophytica subsp. halophytica, NBRC 14112, NRRL 2998
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.