Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCL13011.1methylmalonyl-CoA mutase, N-terminal domain. (562 aa)    
Predicted Functional Partners:
SCL13013.1
LAO/AO transport system kinase.
 0.999
SCL13653.1
methylmalonyl-CoA mutase, C-terminal domain.
 0.998
SCL13016.1
methylmalonyl-CoA epimerase.
 
  
 0.975
SCL30796.1
Glutamate mutase subunit S.
  
 0.903
SCL18177.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.820
SCL13293.1
2-oxoglutarate dehydrogenase E1 component.
   
 
  0.708
SCL16099.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
  0.689
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.684
SCL13630.1
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.680
SCL18174.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.680
Your Current Organism:
Micromonospora inyonensis
NCBI taxonomy Id: 47866
Other names: ATCC 27600, DSM 46123, JCM 3188, M. inyonensis, Micromonospora inyoensis, Micromonospora inyonensis Kroppenstedt et al. 2005, NBRC 13156, NRRL 3292
Server load: low (40%) [HD]