Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCL13835.1uroporphyrinogen-III synthase. (362 aa)    
Predicted Functional Partners:
SCL21836.1
uroporphyrinogen-III C-methyltransferase.
 
 
 0.979
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.973
SCL13830.1
Assimilatory nitrite reductase (NAD(P)H) large subunit precursor; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.955
SCL13833.1
Nitrite reductase [NAD(P)H], small subunit.
 
    0.948
SCL13824.1
Assimilatory nitrate reductase electron transfer subunit.
 
  
 0.940
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.940
SCL13820.1
MFS transporter, NNP family, nitrate/nitrite transporter.
 
  
 0.939
SCL14269.1
uroporphyrinogen-III C-methyltransferase.
  
 
 0.932
SCL13822.1
Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
     0.927
SCL14267.1
Porphobilinogen synthase; Belongs to the ALAD family.
  
 0.921
Your Current Organism:
Micromonospora inyonensis
NCBI taxonomy Id: 47866
Other names: ATCC 27600, DSM 46123, JCM 3188, M. inyonensis, Micromonospora inyoensis, Micromonospora inyonensis Kroppenstedt et al. 2005, NBRC 13156, NRRL 3292
Server load: low (28%) [HD]