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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL17687.1Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (436 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.986
SCL26059.1
5'-3' exonuclease.
   
 0.980
SCL13400.1
ATP-dependent DNA helicase, Rep family.
  
 0.959
SCL22656.1
DNA polymerase III beta subunit, C-terminal domain.
   
 0.897
SCL15841.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
   
 0.894
SCL17689.1
T/G mismatch-specific endonuclease; Manually curated.
 
 
 
 0.893
SCL14159.1
ATP-dependent DNA helicase, RecQ-like.
   
 0.853
SCL24097.1
ATP-dependent DNA helicase RecQ.
   
 0.853
SCL30024.1
ATP-dependent DNA helicase RecQ.
   
 0.853
SCL17692.1
AIPR protein.
 
  
 0.808
Your Current Organism:
Micromonospora inyonensis
NCBI taxonomy Id: 47866
Other names: ATCC 27600, DSM 46123, JCM 3188, M. inyonensis, Micromonospora inyoensis, Micromonospora inyonensis Kroppenstedt et al. 2005, NBRC 13156, NRRL 3292
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