STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL22696.15'-nucleotidase. (279 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.954
SCL22701.1
1-phosphofructokinase.
 
     0.949
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.947
SCL16501.1
LPXTG-motif cell wall anchor domain-containing protein; Belongs to the 5'-nucleotidase family.
  
  
 0.927
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.918
cmk
Cytidylate kinase.
    
 0.915
SCL16267.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.914
purN
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family.
     
 0.908
SCL18576.1
Thymidine phosphorylase.
    
 0.908
pyrF
Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 0.908
Your Current Organism:
Micromonospora inyonensis
NCBI taxonomy Id: 47866
Other names: ATCC 27600, DSM 46123, JCM 3188, M. inyonensis, Micromonospora inyoensis, Micromonospora inyonensis Kroppenstedt et al. 2005, NBRC 13156, NRRL 3292
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