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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL26042.1Malate synthase; Belongs to the malate synthase family. (536 aa)    
Predicted Functional Partners:
SCL26038.1
Isocitrate lyase.
 
 0.999
SCL13298.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.939
SCL13630.1
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.875
SCL17177.1
Citrate synthase; Belongs to the citrate synthase family.
   
 0.854
SCL28762.1
Citrate synthase; Belongs to the citrate synthase family.
   
 0.854
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.853
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.816
SCL27407.1
D-lactate dehydrogenase.
  
 
 0.811
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.755
SCL17501.1
Acetyltransferase (GNAT) domain-containing protein.
   
 
 0.754
Your Current Organism:
Micromonospora inyonensis
NCBI taxonomy Id: 47866
Other names: ATCC 27600, DSM 46123, JCM 3188, M. inyonensis, Micromonospora inyoensis, Micromonospora inyonensis Kroppenstedt et al. 2005, NBRC 13156, NRRL 3292
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