STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (368 aa)    
Predicted Functional Partners:
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.998
SCL70059.1
cob(I)alamin adenosyltransferase.
 
  
 0.983
SCL70075.1
Precorrin-3 methyltransferase /precorrin-2 C20-methyltransferase /cobalt-factor II C20-methyltransferase.
 
 
 0.963
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.962
SCL70072.1
precorrin-8X methylmutase.
 
 
 0.949
SCL70049.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.940
SCL60401.1
Adenosylcobinamide amidohydrolase.
 
  
 0.931
SCL70052.1
precorrin-6Y C5,15-methyltransferase (decarboxylating); Manually curated.
 
  
 0.923
SCL65301.1
ATP:cob(I)alamin adenosyltransferase; Manually curated; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.903
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.896
Your Current Organism:
Micromonospora peucetia
NCBI taxonomy Id: 47871
Other names: DSM 43363, JCM 12820, M. peucetia, Micromonospora peucetia Kroppenstedt et al. 2005, Micromonospora peucetica, NBRC 101886
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.