STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP77459.1Dihydrolipoamide dehydrogenase. (469 aa)    
Predicted Functional Partners:
SEP75631.1
Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.
 
 0.998
SEP75860.1
2-oxoisovalerate dehydrogenase E1 component.
 0.998
SEQ45658.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.996
SER19608.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.996
SEP78185.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
 0.990
SER08566.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.977
SEQ80482.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.967
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.964
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 
 0.940
SEP56213.1
Glutamate synthase (NADH) large subunit.
    
 0.904
Your Current Organism:
Lewinella agarilytica
NCBI taxonomy Id: 478744
Other names: DSM 24740, JBRI 2009, JCM 14216, KCTC 12774, L. agarilytica, Lewinella agarilytica Lee 2007, strain SST-19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.