STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV06243.1Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)    
Predicted Functional Partners:
ACV05322.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain.
 
 0.982
ACV05525.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; e3 binding domain.
 
 0.980
ACV05678.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.953
ACV06649.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.953
ACV06650.1
2-oxoglutarate dehydrogenase E2 component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component).
 
 
 0.939
ACV06325.1
PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.933
ACV05320.1
PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit.
    
 0.928
ACV05527.1
PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit.
    
 0.928
ACV05159.1
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
    
 0.914
ACV06092.1
PFAM: Malic enzyme, N-terminal domain; Malic enzyme, NAD binding domain.
    
 0.914
Your Current Organism:
Kytococcus sedentarius
NCBI taxonomy Id: 478801
Other names: K. sedentarius DSM 20547, Kytococcus sedentarius DSM 20547, Kytococcus sedentarius str. DSM 20547, Kytococcus sedentarius strain DSM 20547
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