STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV07459.1Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (393 aa)    
Predicted Functional Partners:
ACV07570.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.985
ACV05551.1
Methionine synthase II (cobalamin-independent); PFAM: Cobalamin-independent synthase, Catalytic domain.
  
 
 0.976
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.951
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.918
ACV07644.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.915
ACV07289.1
Chorismate mutase, clade 2; PFAM: ACT domain; Prephenate dehydratase; Chorismate mutase type II; Prephenate dehydrogenase; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2.
  
  
 0.785
ACV06486.1
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II.
 
  
 0.630
ACV06529.1
Amino acid adenylation enzyme/thioester reductase family protein; PFAM: AMP-binding enzyme; TIGRFAM: non-ribosomal peptide synthetase terminal domain of unknown function; amino acid adenylation domain.
  
 
 0.563
ACV07458.1
Beta-propeller domain-containing protein, methanol dehydrogenase; PFAM: Domain of unknown function (DUF477).
  
    0.556
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
   
 0.538
Your Current Organism:
Kytococcus sedentarius
NCBI taxonomy Id: 478801
Other names: K. sedentarius DSM 20547, Kytococcus sedentarius DSM 20547, Kytococcus sedentarius str. DSM 20547, Kytococcus sedentarius strain DSM 20547
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