AV274_2127 protein (Blastocystis sp. ATCC 50177Nand)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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[Homology]

Score

AV274_2127

Casein kinase II. (363 aa)

Predicted Functional Partners:

AV274_5141

0.997

AV274_3461

0.943

AV274_2739

0.943

AV274_4015

0.941

AV274_2369

0.923

AV274_0311

0.923

AV274_0199

0.923

AV274_1246

0.921

AV274_2177

0.916

AV274_2091

0.908

Your Current Organism:

Blastocystis sp. ATCC 50177Nand

NCBI taxonomy Id: 478820
Other names: B. sp. ATCC 50177/Nand II, Blastocystis sp. ATCC 50177, Blastocystis sp. ATCC 50177/Nand II, Blastocystis sp. Nand II, Blastocystis sp. NandII, Blastocystis sp. subtype 1 NandII

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AV274_0199	AV274_1246	A0A196SPC2	A0A196SLD4	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	RRP7 domain-containing protein.	0.950
AV274_0199	AV274_2091	A0A196SPC2	A0A196SGG5	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Ankyrin repeat family protein.	0.914
AV274_0199	AV274_2127	A0A196SPC2	A0A196SJT3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II.	0.923
AV274_0199	AV274_2177	A0A196SPC2	A0A196SIG1	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Nucleolar protein 6.	0.947
AV274_0199	AV274_2369	A0A196SPC2	A0A196SFS8	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.403
AV274_0199	AV274_4015	A0A196SPC2	A0A196SDC4	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	FACT complex subunit SPT16.	0.945
AV274_0311	AV274_1246	A0A196SLP6	A0A196SLD4	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	RRP7 domain-containing protein.	0.950
AV274_0311	AV274_2091	A0A196SLP6	A0A196SGG5	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Ankyrin repeat family protein.	0.914
AV274_0311	AV274_2127	A0A196SLP6	A0A196SJT3	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II.	0.923
AV274_0311	AV274_2177	A0A196SLP6	A0A196SIG1	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Nucleolar protein 6.	0.947
AV274_0311	AV274_2369	A0A196SLP6	A0A196SFS8	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.405
AV274_0311	AV274_4015	A0A196SLP6	A0A196SDC4	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	FACT complex subunit SPT16.	0.945
AV274_1246	AV274_0199	A0A196SLD4	A0A196SPC2	RRP7 domain-containing protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.950
AV274_1246	AV274_0311	A0A196SLD4	A0A196SLP6	RRP7 domain-containing protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.950
AV274_1246	AV274_2127	A0A196SLD4	A0A196SJT3	RRP7 domain-containing protein.	Casein kinase II.	0.921
AV274_1246	AV274_2177	A0A196SLD4	A0A196SIG1	RRP7 domain-containing protein.	Nucleolar protein 6.	0.999
AV274_1246	AV274_2369	A0A196SLD4	A0A196SFS8	RRP7 domain-containing protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.950
AV274_2091	AV274_0199	A0A196SGG5	A0A196SPC2	Ankyrin repeat family protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.914
AV274_2091	AV274_0311	A0A196SGG5	A0A196SLP6	Ankyrin repeat family protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.914
AV274_2091	AV274_2127	A0A196SGG5	A0A196SJT3	Ankyrin repeat family protein.	Casein kinase II.	0.908

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Network Stats

number of nodes:

5

number of edges:

5

average node degree:

2

avg. local clustering coefficient:

0.833

expected number of edges:

4

PPI enrichment p-value:

0.376

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000455

Enzyme-directed rRNA pseudouridine synthesis

3 of 4

2.45

1.74

0.00059

GO:0007059

Chromosome segregation

3 of 8

2.15

1.68

0.00059

GO:0042254

Ribosome biogenesis

4 of 29

1.71

1.5

0.00059

GO:0044085

Cellular component biogenesis

5 of 105

1.25

1.12

0.00067

GO:0007049

Cell cycle

3 of 27

1.62

1.07

0.0056

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0120159

rRNA pseudouridine synthase activity

3 of 4

2.45

1.87

0.00033

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:965

Pseudouridine synthase, RsuA/RluB/E/F, and Chromosome segregation

7 of 7

2.57

6.33

2.55e-13

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0159

Chromosome partition

2 of 5

2.18

1.07

0.0102

KW-0132

Cell division

3 of 26

1.64

0.97

0.0102

KW-0131

Cell cycle

3 of 26

1.64

0.97

0.0102

KW-0963

Cytoplasm

5 of 226

0.92

0.62

0.0102

KW-0413

Isomerase

3 of 74

1.18

0.61

0.0379

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR042092

Pseudouridine synthase, RsuA/RluB/E/F, catalytic domain

3 of 3

2.57

1.83

0.00043

IPR018496

Pseudouridine synthase, RsuA/RluB/E/F, conserved site

3 of 3

2.57

1.83

0.00043

IPR000748

Pseudouridine synthase, RsuA/RluB/E/F

3 of 3

2.57

1.83

0.00043

IPR020094

Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal

3 of 4

2.45

1.81

0.00043

IPR006145

Pseudouridine synthase, RsuA/RluA-like

3 of 7

2.21

1.72

0.00051

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00363

S4 RNA-binding domain

2 of 6

2.1

0.88

0.0226

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