STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEB64444.1Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (282 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
 
 
 0.997
SEC99572.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.997
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.909
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 0.896
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
 0.801
SEB77164.1
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
     
 0.756
SEC37165.1
Nicotinamide-nucleotide adenylyltransferase, NadR type.
     
 0.756
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     0.747
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.739
SEB42828.1
Putative hydrolase of the HAD superfamily.
  
  
 0.737
Your Current Organism:
Pseudomonas taetrolens
NCBI taxonomy Id: 47884
Other names: ATCC 4683, CCUG 560, CFBP 5592, CIP 103299, JCM 20238, LMG 2336, LMG:2336, NCIB 9396, NCIB:9396, NCTC 10697, NRRL B-14, NRRL B-731, NRRL:B:14, NRRL:B:731, P. taetrolens, VKM B-904, VKM:B:904
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