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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (336 aa)    
Predicted Functional Partners:
SED60525.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 0.995
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.977
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.957
SEC54700.1
3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase).
 
  
 0.942
SED09241.1
Arabinose-5-phosphate isomerase.
 
   
 0.886
SEC54758.1
Arabinose-5-phosphate isomerase.
 
   
 0.882
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.865
SED01530.1
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase.
 
   
 0.859
lpxA
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.853
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family.
 
   
 0.850
Your Current Organism:
Pseudomonas taetrolens
NCBI taxonomy Id: 47884
Other names: ATCC 4683, CCUG 560, CFBP 5592, CIP 103299, JCM 20238, LMG 2336, LMG:2336, NCIB 9396, NCIB:9396, NCTC 10697, NRRL B-14, NRRL B-731, NRRL:B:14, NRRL:B:731, P. taetrolens, VKM B-904, VKM:B:904
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