| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEB57037.1 | SEC71774.1 | SAMN04490203_0670 | SAMN04490203_2972 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.665 |
| SEB57037.1 | SED56839.1 | SAMN04490203_0670 | SAMN04490203_4189 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Curved DNA-binding protein. | 0.832 |
| SEB57037.1 | dnaJ | SAMN04490203_0670 | SAMN04490203_3977 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.829 |
| SEB57037.1 | dnaK | SAMN04490203_0670 | SAMN04490203_3978 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.963 |
| SEB57037.1 | groEL | SAMN04490203_0670 | SAMN04490203_1168 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.667 |
| SEB57037.1 | grpE | SAMN04490203_0670 | SAMN04490203_3979 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.831 |
| SEB57037.1 | htpG | SAMN04490203_0670 | SAMN04490203_1565 | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.689 |
| SEB70435.1 | SED56839.1 | SAMN04490203_0997 | SAMN04490203_4189 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Curved DNA-binding protein. | 0.429 |
| SEB70435.1 | dnaJ | SAMN04490203_0997 | SAMN04490203_3977 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.494 |
| SEB70435.1 | dnaK | SAMN04490203_0997 | SAMN04490203_3978 | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.965 |
| SEC71774.1 | SEB57037.1 | SAMN04490203_2972 | SAMN04490203_0670 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | 0.665 |
| SEC71774.1 | SED56839.1 | SAMN04490203_2972 | SAMN04490203_4189 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Curved DNA-binding protein. | 0.971 |
| SEC71774.1 | clpA | SAMN04490203_2972 | SAMN04490203_1609 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.665 |
| SEC71774.1 | clpB | SAMN04490203_2972 | SAMN04490203_0851 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.665 |
| SEC71774.1 | dnaJ | SAMN04490203_2972 | SAMN04490203_3977 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.971 |
| SEC71774.1 | dnaK | SAMN04490203_2972 | SAMN04490203_3978 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.985 |
| SEC71774.1 | groEL | SAMN04490203_2972 | SAMN04490203_1168 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.930 |
| SEC71774.1 | grpE | SAMN04490203_2972 | SAMN04490203_3979 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.801 |
| SED56839.1 | SEB57037.1 | SAMN04490203_4189 | SAMN04490203_0670 | Curved DNA-binding protein. | Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. | 0.832 |
| SED56839.1 | SEB70435.1 | SAMN04490203_4189 | SAMN04490203_0997 | Curved DNA-binding protein. | FeS assembly scaffold apoprotein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.429 |
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