| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ83113.1 | ALZ83117.1 | APT59_02445 | APT59_02465 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
| ALZ83113.1 | ALZ86259.1 | APT59_02445 | APT59_19370 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
| ALZ83113.1 | ureB | APT59_02445 | APT59_18650 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.454 |
| ALZ83113.1 | ureD | APT59_02445 | APT59_18635 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.456 |
| ALZ83113.1 | ureE | APT59_02445 | APT59_02460 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.794 |
| ALZ83113.1 | ureF | APT59_02445 | APT59_02455 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.816 |
| ALZ83113.1 | ureG | APT59_02445 | APT59_02450 | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.819 |
| ALZ83117.1 | ALZ83113.1 | APT59_02465 | APT59_02445 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
| ALZ83117.1 | ureE | APT59_02465 | APT59_02460 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.586 |
| ALZ83117.1 | ureF | APT59_02465 | APT59_02455 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.586 |
| ALZ83117.1 | ureG | APT59_02465 | APT59_02450 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.580 |
| ALZ86259.1 | ALZ83113.1 | APT59_19370 | APT59_02445 | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
| ureB | ALZ83113.1 | APT59_18650 | APT59_02445 | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.454 |
| ureB | ureD | APT59_18650 | APT59_18635 | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.984 |
| ureB | ureE | APT59_18650 | APT59_02460 | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.881 |
| ureB | ureF | APT59_18650 | APT59_02455 | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.932 |
| ureB | ureG | APT59_18650 | APT59_02450 | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.942 |
| ureD | ALZ83113.1 | APT59_18635 | APT59_02445 | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.456 |
| ureD | ureB | APT59_18635 | APT59_18650 | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.984 |
| ureD | ureE | APT59_18635 | APT59_02460 | Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.967 |