| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ84309.1 | ALZ84310.1 | APT59_08845 | APT59_08850 | Methyltransferase type 12; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
| ALZ84310.1 | ALZ84309.1 | APT59_08850 | APT59_08845 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase type 12; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
| ALZ84310.1 | ALZ84802.1 | APT59_08850 | APT59_11575 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | 0.663 |
| ALZ84310.1 | ALZ85768.1 | APT59_08850 | APT59_16730 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family. | 0.860 |
| ALZ84310.1 | mnmE | APT59_08850 | APT59_00120 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.697 |
| ALZ84310.1 | obgE | APT59_08850 | APT59_17975 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.677 |
| ALZ84310.1 | rplC | APT59_08850 | APT59_20070 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.665 |
| ALZ84310.1 | rplM | APT59_08850 | APT59_15890 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.647 |
| ALZ84310.1 | rplU | APT59_08850 | APT59_17985 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.695 |
| ALZ84310.1 | rplX | APT59_08850 | APT59_20015 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.654 |
| ALZ84310.1 | rsfS | APT59_08850 | APT59_05245 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.648 |
| ALZ84802.1 | ALZ84310.1 | APT59_11575 | APT59_08850 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| ALZ85768.1 | ALZ84310.1 | APT59_16730 | APT59_08850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.860 |
| mnmE | ALZ84310.1 | APT59_00120 | APT59_08850 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.697 |
| mnmE | obgE | APT59_00120 | APT59_17975 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.710 |
| mnmE | rplC | APT59_00120 | APT59_20070 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.677 |
| mnmE | rplM | APT59_00120 | APT59_15890 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.777 |
| mnmE | rplU | APT59_00120 | APT59_17985 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.814 |
| mnmE | rplX | APT59_00120 | APT59_20015 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.697 |
| mnmE | rsfS | APT59_00120 | APT59_05245 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.786 |