| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ82841.1 | polA | APT59_00960 | APT59_00725 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.703 |
| ALZ82841.1 | recA | APT59_00960 | APT59_06330 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.555 |
| ALZ82841.1 | recD | APT59_00960 | APT59_17740 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.411 |
| ALZ82841.1 | recQ | APT59_00960 | APT59_09645 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.943 |
| ALZ83112.1 | ALZ84812.1 | APT59_02440 | APT59_11635 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| ALZ83112.1 | polA | APT59_02440 | APT59_00725 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.952 |
| ALZ83112.1 | recA | APT59_02440 | APT59_06330 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.588 |
| ALZ83112.1 | recQ | APT59_02440 | APT59_09645 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| ALZ83112.1 | topA | APT59_02440 | APT59_16595 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.432 |
| ALZ84812.1 | ALZ83112.1 | APT59_11635 | APT59_02440 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| ALZ84812.1 | polA | APT59_11635 | APT59_00725 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.494 |
| ALZ84812.1 | recQ | APT59_11635 | APT59_09645 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.733 |
| deaD | recQ | APT59_11735 | APT59_09645 | RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| mutL | polA | APT59_19590 | APT59_00725 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.944 |
| mutL | recA | APT59_19590 | APT59_06330 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.640 |
| mutL | recD | APT59_19590 | APT59_17740 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.491 |
| mutL | recQ | APT59_19590 | APT59_09645 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| mutL | topA | APT59_19590 | APT59_16595 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.500 |
| polA | ALZ82841.1 | APT59_00725 | APT59_00960 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| polA | ALZ83112.1 | APT59_00725 | APT59_02440 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |