| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ82697.1 | ALZ84749.1 | APT59_00200 | APT59_11285 | 16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 0.576 |
| ALZ82697.1 | ALZ85171.1 | APT59_00200 | APT59_13570 | 16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.690 |
| ALZ82697.1 | thiI | APT59_00200 | APT59_20455 | 16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.862 |
| ALZ83266.1 | ALZ84749.1 | APT59_03295 | APT59_11285 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 0.430 |
| ALZ83266.1 | miaB | APT59_03295 | APT59_05355 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.526 |
| ALZ83517.1 | ALZ84749.1 | APT59_04610 | APT59_11285 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 0.437 |
| ALZ83517.1 | ALZ85171.1 | APT59_04610 | APT59_13570 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.491 |
| ALZ83517.1 | ribD | APT59_04610 | APT59_19865 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.500 |
| ALZ83517.1 | thiI | APT59_04610 | APT59_20455 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.433 |
| ALZ84748.1 | ALZ84749.1 | APT59_11280 | APT59_11285 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 0.602 |
| ALZ84749.1 | ALZ82697.1 | APT59_11285 | APT59_00200 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.576 |
| ALZ84749.1 | ALZ83266.1 | APT59_11285 | APT59_03295 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.430 |
| ALZ84749.1 | ALZ83517.1 | APT59_11285 | APT59_04610 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| ALZ84749.1 | ALZ84748.1 | APT59_11285 | APT59_11280 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
| ALZ84749.1 | ALZ84750.1 | APT59_11285 | APT59_11290 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.531 |
| ALZ84749.1 | ALZ85171.1 | APT59_11285 | APT59_13570 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| ALZ84749.1 | miaB | APT59_11285 | APT59_05355 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.586 |
| ALZ84749.1 | nusB | APT59_11285 | APT59_19845 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.452 |
| ALZ84749.1 | ribD | APT59_11285 | APT59_19865 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.531 |
| ALZ84749.1 | thiI | APT59_11285 | APT59_20455 | 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the radical SAM superfamily. RlmN family. | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.440 |