| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ82967.1 | ALZ83366.1 | APT59_01620 | APT59_03800 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
| ALZ82967.1 | ALZ86466.1 | APT59_01620 | APT59_20475 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.842 |
| ALZ82967.1 | ALZ86901.1 | APT59_01620 | APT59_16985 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
| ALZ82967.1 | glnA | APT59_01620 | APT59_20460 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.789 |
| ALZ82967.1 | gltB | APT59_01620 | APT59_03160 | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
| ALZ83366.1 | ALZ82967.1 | APT59_03800 | APT59_01620 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
| ALZ83366.1 | ALZ84102.1 | APT59_03800 | APT59_07695 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
| ALZ83366.1 | ALZ84104.1 | APT59_03800 | APT59_07705 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.880 |
| ALZ83366.1 | ALZ85325.1 | APT59_03800 | APT59_14390 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.814 |
| ALZ83366.1 | ALZ85690.1 | APT59_03800 | APT59_16325 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| ALZ83366.1 | ALZ86901.1 | APT59_03800 | APT59_16985 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.609 |
| ALZ83366.1 | gltB | APT59_03800 | APT59_03160 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.702 |
| ALZ84102.1 | ALZ83366.1 | APT59_07695 | APT59_03800 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
| ALZ84102.1 | ALZ84104.1 | APT59_07695 | APT59_07705 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
| ALZ84102.1 | ALZ85325.1 | APT59_07695 | APT59_14390 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.947 |
| ALZ84102.1 | ALZ85690.1 | APT59_07695 | APT59_16325 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| ALZ84102.1 | ALZ86466.1 | APT59_07695 | APT59_20475 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| ALZ84102.1 | ALZ86901.1 | APT59_07695 | APT59_16985 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.487 |
| ALZ84102.1 | glnA | APT59_07695 | APT59_20460 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
| ALZ84102.1 | gltB | APT59_07695 | APT59_03160 | Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.727 |