| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ85793.1 | ALZ86532.1 | APT59_16855 | APT59_20825 | NAD(P)H-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| ALZ85793.1 | ribF | APT59_16855 | APT59_17955 | NAD(P)H-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.918 |
| ALZ85988.1 | ileS | APT59_17940 | APT59_17950 | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.843 |
| ALZ85988.1 | lspA | APT59_17940 | APT59_17945 | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.873 |
| ALZ85988.1 | mviN | APT59_17940 | APT59_17960 | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Murein biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.595 |
| ALZ85988.1 | ribF | APT59_17940 | APT59_17955 | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.805 |
| ALZ86350.1 | ALZ86532.1 | APT59_19860 | APT59_20825 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| ALZ86350.1 | ribF | APT59_19860 | APT59_17955 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.945 |
| ALZ86350.1 | ribH | APT59_19860 | APT59_19850 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.999 |
| ALZ86532.1 | ALZ85793.1 | APT59_20825 | APT59_16855 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD(P)H-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| ALZ86532.1 | ALZ86350.1 | APT59_20825 | APT59_19860 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| ALZ86532.1 | ribF | APT59_20825 | APT59_17955 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.909 |
| ALZ86532.1 | ribH | APT59_20825 | APT59_19850 | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.905 |
| cmk | ribF | APT59_14835 | APT59_17955 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.834 |
| ileS | ALZ85988.1 | APT59_17950 | APT59_17940 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.843 |
| ileS | lspA | APT59_17950 | APT59_17945 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.909 |
| ileS | mviN | APT59_17950 | APT59_17960 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Murein biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.595 |
| ileS | ribF | APT59_17950 | APT59_17955 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.817 |
| ileS | truB | APT59_17950 | APT59_02355 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.485 |
| lspA | ALZ85988.1 | APT59_17945 | APT59_17940 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Peptidylprolyl isomerase; Rotamase; accelerates isomerization of the peptidyl prolyl bond, involved in the folding of proteases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |