| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ83863.1 | ALZ84822.1 | APT59_06440 | APT59_11685 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.741 |
| ALZ83863.1 | ALZ86256.1 | APT59_06440 | APT59_19355 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.748 |
| ALZ83863.1 | ALZ86257.1 | APT59_06440 | APT59_19360 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| ALZ83863.1 | ALZ86259.1 | APT59_06440 | APT59_19370 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.964 |
| ALZ83863.1 | ALZ86260.1 | APT59_06440 | APT59_19375 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-5B (C(1))-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
| ALZ83863.1 | ALZ86261.1 | APT59_06440 | APT59_19380 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6A reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
| ALZ83863.1 | cobJ | APT59_06440 | APT59_19350 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| ALZ83863.1 | cobM | APT59_06440 | APT59_19385 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| ALZ83863.1 | cobQ | APT59_06440 | APT59_07140 | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.784 |
| ALZ83999.1 | ALZ86256.1 | APT59_07145 | APT59_19355 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.432 |
| ALZ83999.1 | ALZ86257.1 | APT59_07145 | APT59_19360 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
| ALZ83999.1 | ALZ86259.1 | APT59_07145 | APT59_19370 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.781 |
| ALZ83999.1 | ALZ86260.1 | APT59_07145 | APT59_19375 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cobalt-precorrin-5B (C(1))-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
| ALZ83999.1 | ALZ86261.1 | APT59_07145 | APT59_19380 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cobalt-precorrin-6A reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
| ALZ83999.1 | cobJ | APT59_07145 | APT59_19350 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
| ALZ83999.1 | cobM | APT59_07145 | APT59_19385 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| ALZ83999.1 | cobQ | APT59_07145 | APT59_07140 | Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| ALZ84822.1 | ALZ83863.1 | APT59_11685 | APT59_06440 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin 6A synthase; Catalyzes the formation of precorrin 6x from precorrin 5; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.741 |
| ALZ84822.1 | ALZ86256.1 | APT59_11685 | APT59_19355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.746 |
| ALZ84822.1 | ALZ86257.1 | APT59_11685 | APT59_19360 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |