| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALZ85748.1 | rplA | APT59_16620 | APT59_20120 | ABC transporter ATP-binding protein; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.580 |
| ALZ85748.1 | rpsJ | APT59_16620 | APT59_20075 | ABC transporter ATP-binding protein; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.580 |
| ALZ85748.1 | typA | APT59_16620 | APT59_20450 | ABC transporter ATP-binding protein; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.596 |
| ALZ85748.1 | ychF | APT59_16620 | APT59_02755 | ABC transporter ATP-binding protein; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.442 |
| gltB | guaA | APT59_03160 | APT59_16090 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.898 |
| gltB | thiI | APT59_03160 | APT59_20455 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.645 |
| gltB | typA | APT59_03160 | APT59_20450 | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.736 |
| guaA | gltB | APT59_16090 | APT59_03160 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamate synthase large subunit; Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.898 |
| guaA | infC | APT59_16090 | APT59_07250 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 0.514 |
| guaA | rimP | APT59_16090 | APT59_02335 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.417 |
| guaA | rplA | APT59_16090 | APT59_20120 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.953 |
| guaA | rpsJ | APT59_16090 | APT59_20075 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.663 |
| guaA | thiI | APT59_16090 | APT59_20455 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.724 |
| guaA | tsf | APT59_16090 | APT59_06125 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.677 |
| guaA | typA | APT59_16090 | APT59_20450 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
| guaA | ychF | APT59_16090 | APT59_02755 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.803 |
| infC | guaA | APT59_07250 | APT59_16090 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.514 |
| infC | rplA | APT59_07250 | APT59_20120 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.930 |
| infC | rpsJ | APT59_07250 | APT59_20075 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.960 |
| infC | tsf | APT59_07250 | APT59_06125 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.933 |