STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaYIron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (109 aa)    
Predicted Functional Partners:
ALZ85709.1
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.982
hscB
Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.916
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.909
hscA
2Fe-2S ferredoxin; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 0.895
ALZ85693.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.875
iscX
Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.808
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
   
 
 0.614
ALZ86532.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.610
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 
 0.605
ALZ86493.1
CDP-6-deoxy-delta-3,4-glucoseen reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.596
Your Current Organism:
Pseudomonas oryzihabitans
NCBI taxonomy Id: 47885
Other names: AJ 2197, ATCC 43272, CCUG 12540, CIP 102996, DSM 6835, Flavimonas oryzihabitans, JCM 2952, LMG 7040, LMG:7040, NBRC 102199, P. oryzihabitans, group Ve-2, strain KS0036
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