STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AM587_10014768E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2285 aa)    
Predicted Functional Partners:
AM587_10013678
E3 ubiquitin-protein ligase TRIP12.
   
 0.959
AM587_10017789
Ankyrin repeat and FYVE domain-containing protein 1.
   
 0.959
AM587_10011380
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.855
AM587_10008633
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
    
 0.527
AM587_10014170
NEDD8-activating enzyme E1 catalytic subunit.
    
 0.527
AM587_10000787
HNHc domain-containing protein.
   
 0.487
AM587_10011988
Ubiquitin-like domain-containing protein.
   
 0.456
AM587_10007951
40S ribosomal protein S30.
   
 0.456
AM587_10015375
Phosphatidylinositol 4-kinase gamma 5.
   
 0.456
AM587_10006403
Polyubiquitin-B.
   
 0.456
Your Current Organism:
Phytophthora nicotianae
NCBI taxonomy Id: 4790
Other names: P. nicotianae, buckeye rot agent
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.