Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AM587_10006440alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (698 aa)    
Predicted Functional Partners:
AM587_10016045
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
 
0.967
AM587_10010433
Heat shock 70 kDa protein 17.
    
 
 0.850
AM587_10014124
Heat shock 70 kDa protein 17.
    
 
 0.850
AM587_10012573
NADH dehydrogenase iron-sulfur protein 7.
    
   0.804
AM587_10010920
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
    
 
 0.743
AM587_10012157
Uncharacterized protein.
    
 
 0.737
AM587_10017780
ER membrane protein complex subunit 3.
    
 
 0.705
AM587_10012677
Neutral alpha-glucosidase AB; Belongs to the glycosyl hydrolase 31 family.
    
 
 0.698
AM587_10010160
Calnexin 1.
    
 
 0.663
AM587_10003820
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 
 0.657
Your Current Organism:
Phytophthora nicotianae
NCBI taxonomy Id: 4790
Other names: P. nicotianae, buckeye rot agent
Server load: low (16%) [HD]