STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AM587_10012987DNA repair endonuclease XPF. (1245 aa)    
Predicted Functional Partners:
AM587_10016640
DNA excision repair protein ERCC-1.
   
 0.969
AM587_10008807
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.955
AM587_10014367
DNA repair protein.
    
 0.954
AM587_10014411
E3 ubiquitin-protein ligase FANCL.
    
 0.947
AM587_10002081
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.908
AM587_10011842
NPL4 protein.
   
 0.906
AM587_10010074
Replication protein A subunit.
    
 0.881
AM587_10010667
Replication protein A 70 kDa DNA-binding subunit.
    
 0.881
AM587_10010460
Replication protein A 70 kDa DNA-binding subunit.
    
 0.881
AM587_10007194
Telomere length regulation protein TEL2.
   
 
 0.849
Your Current Organism:
Phytophthora nicotianae
NCBI taxonomy Id: 4790
Other names: P. nicotianae, buckeye rot agent
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