node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AM587_10002081 | AM587_10008807 | A0A0W8CJ55 | A0A0W8CDU0 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.425 |
AM587_10002081 | AM587_10010074 | A0A0W8CJ55 | A0A0W8BZZ9 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Replication protein A subunit. | 0.510 |
AM587_10002081 | AM587_10010460 | A0A0W8CJ55 | A0A0W8CWU2 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Replication protein A 70 kDa DNA-binding subunit. | 0.510 |
AM587_10002081 | AM587_10010667 | A0A0W8CJ55 | A0A0W8C0H1 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | Replication protein A 70 kDa DNA-binding subunit. | 0.510 |
AM587_10002081 | AM587_10011842 | A0A0W8CJ55 | A0A0W8C886 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | NPL4 protein. | 0.955 |
AM587_10002081 | AM587_10012987 | A0A0W8CJ55 | A0A0W8CQU8 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | DNA repair endonuclease XPF. | 0.908 |
AM587_10002081 | AM587_10014411 | A0A0W8CJ55 | A0A0W8BX43 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | E3 ubiquitin-protein ligase FANCL. | 0.911 |
AM587_10002081 | AM587_10016640 | A0A0W8CJ55 | A0A0W8D380 | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | DNA excision repair protein ERCC-1. | 0.789 |
AM587_10007194 | AM587_10012987 | A0A0W8C9E1 | A0A0W8CQU8 | Telomere length regulation protein TEL2. | DNA repair endonuclease XPF. | 0.849 |
AM587_10007194 | AM587_10016640 | A0A0W8C9E1 | A0A0W8D380 | Telomere length regulation protein TEL2. | DNA excision repair protein ERCC-1. | 0.760 |
AM587_10008807 | AM587_10002081 | A0A0W8CDU0 | A0A0W8CJ55 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.425 |
AM587_10008807 | AM587_10010074 | A0A0W8CDU0 | A0A0W8BZZ9 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit. | 0.916 |
AM587_10008807 | AM587_10010460 | A0A0W8CDU0 | A0A0W8CWU2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A 70 kDa DNA-binding subunit. | 0.916 |
AM587_10008807 | AM587_10010667 | A0A0W8CDU0 | A0A0W8C0H1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A 70 kDa DNA-binding subunit. | 0.916 |
AM587_10008807 | AM587_10011842 | A0A0W8CDU0 | A0A0W8C886 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | NPL4 protein. | 0.876 |
AM587_10008807 | AM587_10012987 | A0A0W8CDU0 | A0A0W8CQU8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair endonuclease XPF. | 0.955 |
AM587_10008807 | AM587_10016640 | A0A0W8CDU0 | A0A0W8D380 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA excision repair protein ERCC-1. | 0.568 |
AM587_10010074 | AM587_10002081 | A0A0W8BZZ9 | A0A0W8CJ55 | Replication protein A subunit. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.510 |
AM587_10010074 | AM587_10008807 | A0A0W8BZZ9 | A0A0W8CDU0 | Replication protein A subunit. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.916 |
AM587_10010074 | AM587_10012987 | A0A0W8BZZ9 | A0A0W8CQU8 | Replication protein A subunit. | DNA repair endonuclease XPF. | 0.881 |