STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AM587_10003006DUF21 domain-containing protein. (485 aa)    
Predicted Functional Partners:
AM587_10003573
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.673
AM587_10005639
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.647
AM587_10007764
MGS domain-containing protein.
    
 0.638
AM587_10003714
Urease accessory protein UreD.
    
 0.638
AM587_10017716
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.621
AM587_10002321
Protein tyrosine phosphatase type IVA A.
    
 
 0.608
AM587_10003546
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.584
AM587_10000044
Trifunctional nucleotide phosphoesterase protein YfkN.
    
  0.584
AM587_10003477
Trifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family.
    
  0.584
AM587_10011041
Trifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family.
    
  0.584
Your Current Organism:
Phytophthora nicotianae
NCBI taxonomy Id: 4790
Other names: P. nicotianae, buckeye rot agent
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.