STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AM587_100106022-hydroxyacid dehydrogenase 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)    
Predicted Functional Partners:
AM587_10011273
Tryptophan synthase.
  
 0.886
AM587_10011938
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.704
AM587_10014477
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
   
 0.701
AM587_10003709
Acetolactate synthase.
  
 
 0.695
AM587_10013195
Malate synthase; Belongs to the malate synthase family.
    
 0.689
AM587_10005488
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.684
AM587_10005754
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.681
AM587_10014777
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.678
AM587_10005921
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.669
AM587_10016758
Hydroxyacylglutathione hydrolase protein.
     
 0.660
Your Current Organism:
Phytophthora nicotianae
NCBI taxonomy Id: 4790
Other names: P. nicotianae, buckeye rot agent
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