Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
btuFCobalamin-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (268 aa)    
Predicted Functional Partners:
btuC
Vtamin B12-transporter permease; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
 
 
 0.998
btuD
Vitamin B12 ABC transporter ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
  
 
 0.969
mtnN
5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/U [...]
  
  
 0.859
ALX94931.1
Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.853
ALX93480.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.836
ALX96397.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.834
ALX93669.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.815
ALX96147.1
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.802
ALX96670.1
Iron-hydroxamate transporter ATP-binding subunit; Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.801
ALX96146.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.798
Your Current Organism:
Serratia fonticola
NCBI taxonomy Id: 47917
Other names: ATCC 29844, CCUG 14186, CCUG 37824, CCUG 57457 [[Serratia glossinae]], CIP 78.64, DSM 22080 [[Serratia glossinae]], DSM 4576, LMG 7882, LMG:7882, NBRC 102597, NCTC 12965, S. fonticola, Serratia glossinae, Serratia glossinae Geiger et al. 2010, strain 11, strain C1 [[Serratia glossinae]]
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