STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)    
Predicted Functional Partners:
Namu_4703
Citrate synthase I; KEGG: scl:sce8281 hypothetical protein; TIGRFAM: citrate synthase I; PFAM: Citrate synthase.
  
 0.987
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.984
Namu_4708
PFAM: Citrate synthase; KEGG: pzu:PHZ_c0162 citrate synthase GltA; Belongs to the citrate synthase family.
  
 0.982
Namu_2341
PFAM: Lactate/malate dehydrogenase; KEGG: mpt:Mpe_B0497 malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily.
   
 
 0.974
Namu_0045
KEGG: vei:Veis_2009 citrate synthase.
  
 0.961
Namu_1877
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.958
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
 
  
 0.955
Namu_0264
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme.
  
 0.943
Namu_1302
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: mca:MCA1836 malate dehydrogenase.
  
 0.943
Namu_1419
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: tau:Tola_0213 malate dehydrogenase (oxaloacetate-decarboxylating).
  
 0.943
Your Current Organism:
Nakamurella multipartita
NCBI taxonomy Id: 479431
Other names: N. multipartita DSM 44233, Nakamurella multipartita DSM 44233, Nakamurella multipartita str. DSM 44233, Nakamurella multipartita strain DSM 44233
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