STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_1254KEGG: oca:OCAR_5440 isocitrate dehydrogenase, NADP- dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)    
Predicted Functional Partners:
Sros_8284
KEGG: sus:Acid_5307 alpha-ketoglutarate decarboxylase.
  
 
 0.993
Sros_6743
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.990
Sros_8500
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.968
Sros_0661
KEGG: afw:Anae109_1891 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.954
Sros_2949
KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin).
    
 0.949
Sros_2327
KEGG: sus:Acid_0039 glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.946
Sros_5524
KEGG: ade:Adeh_3019 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.946
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.937
Sros_1252
KEGG: aca:ACP_1789 citrate synthase 2; Belongs to the citrate synthase family.
  
 
 0.935
Sros_0660
KEGG: eba:ebA3150 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.919
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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