STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_1733Metal-dependent hydrolase of the beta-lactamase superfamily III-like protein; KEGG: baa:BA_1639 lactamase_B, metallo-beta- lactamase superfamily. (250 aa)    
Predicted Functional Partners:
Sros_5160
KEGG: dat:HRM2_43210 hypothetical protein.
   
   0.905
rph
tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.882
Sros_1735
HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
    0.859
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
     0.736
Sros_8980
Adenylate cyclase family 3 (some protein contain HAMP domain)-like protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase.
     
 0.659
Sros_6530
KEGG: mxa:MXAN_6717 putative ATP-dependent helicase.
 
  
 0.553
Sros_0468
Putative transcriptional regulator, Crp/Fnr family; KEGG: bra:BRADO5298 transcriptional regulator.
 
   
 0.534
Sros_1731
KEGG: dal:Dalk_1857 hypothetical protein.
       0.454
Sros_1736
Hypothetical protein.
       0.434
Sros_1737
KEGG: Hypothetical protein CBG04553.
       0.434
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.