STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_3577KEGG: baa:BA_0525 carbon starvation protein CstA. (712 aa)    
Predicted Functional Partners:
Sros_3578
Hypothetical protein.
       0.832
Sros_3971
KEGG: avi:Avi_5820 monocarboxylic acid permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.827
Sros_3097
KEGG: baa:BA_0116 proline dehydrogenase.
   
  
 0.538
Sros_3332
KEGG: bha:BH1939 proline dehydrogenase.
   
  
 0.538
Sros_3870
KEGG: met:M446_4772 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
  
 0.538
pxpA
Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.528
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  
 0.526
Sros_1444
KEGG: rme:Rmet_2699 acetyl-CoA synthetase.
   
  
 0.526
Sros_1890
KEGG: rce:RC1_1843 propionate--CoA ligase.
   
  
 0.526
Sros_3763
KEGG: bxe:Bxe_A1419 benzoate-coenzyme A ligase.
   
  
 0.526
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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